Starbios2 is a four-year project (2016-2020) within the European Commissions Science with and for Society HORIZON 2020 Programme, focusing on Responsible Research and Innovation (RRI). Nine research institutions from European countries and three international partners are involved in the project coordinated by the Università degli studi di Roma Tor Vergata in Italy. The project has the following main objectives: 1) Develop RRI-oriented structural change processes, by designing, implementing and evaluating six RRI Action Plans (APs) in research institutions from Europe (in Bulgaria, Germany, Italy, Poland, Slovenia and the United Kingdom), and developing three further APs in non-European entities (in Brazil, South Africa and the United States), all active in the field of biosciences. Within the APs, five RRI issues are considered: public engagement, gender, education, open access and ethics. 2) Develop a learning process on RRI-oriented structural change, based on the implementation of APs. The following issues are considered: resistances and barriers to RRI; key factors favouring or supporting RRI; and strategic options and RRI-oriented tools. The outputs of the learning process will result in the development of a set of recommendations on how to support RRI in research institutions. 3) Develop a sustainable model for RRI in the biosciences. The model would provide the staff and leaders of Biosciences Departments and Divisions with further and better formalised orientations and practical knowledge about the key issues related to the implementation of RRI and how they can be encompassed.

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