This book not only introduces the reader to the necessary tools to understand microbiome but also discusses many relevant areas of current research and applications of microbiome engineering, ranging from human diseases to husbandry, food and beverage applications.

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Matthew Chang is Associate Professor in Biochemistry in the Yong Loo Lin School of Medicine at the National University of Singapore (NUS), and Director of the Singapore Consortium for Synthetic Biology (SINERGY), Wilmar-NUS Corporate Laboratory (Wil-NUS) and NUS Synthetic Biology for Clinical and Technological Innovation (SynCTI). His research interests lie in the development of biological systems that perform programmable functions. In particular, he has pioneered the development of microbial cells programmed to perform targeted therapeutic functionalities. His scientific contributions have been recognized with international honours and awards, including the Scientific and Technological Achievement Award from U.S. Environmental Protection Agency, and featured in leading media outlets worldwide. He serves as an editor and an editorial board member for a number of journals including Cell Systems, Metabolic Engineering, Biotechnology for Biofuels, ACS Synthetic Biology, and Critical Reviews in Microbiology. He serves on the advisory committee of key international research programs such as the Synthetic Biology Open Language (SBOL) and CSIRO Future Science Platform.

Leseprobe

Section I: Advancing understanding of microbiome Chapter 1: Systems biology and microbiomeChapter 2: Synthetic biology and microbiomeChapter 3: Computational modelling of microbiome and host-microbiome interactionsChapter 4: Machine learning of the microbiome big data Section II: Microbiome engineering Chapter 5: Human microbiome engineering against pathogen infectionsChapter 6: Human microbiome engineering against cancerChapter 7: Human microbiome engineering against diabetesChapter 8: Human microbiome engineering against obesityChapter 9: Human microbiome engineering against mental disordersChapter 10: Human microbiome engineering against autoimmune and inflammatory disordersChapter 11: Husbandry microbiome engineeringChapter 12: Plant-soil microbiome engineeringChapter 13: Food microbiome engineeringChapter 14: Beverage microbiome engineering Section III: Perspectives on microbiome engineering Chapter 15: Future perspectives on Microbiome and its applications