This symposium on cerebral and coronary vascular disorders and infarcts is probably the first attempt to hold a joint discussion in this field. Despite many difficulties we feel that it has been successful and we hope that it will stimulate further interest and investigations. To hold such a meeting with scientists from far away was possible only with the assistance of Bundesminister fUr Jugend, Familie und Gesundheit, Minister fUr Hissenschaft und Forschung des Lan­ des Nordrhein-Westfalen, Max-Planck-Gesellschaft zur Forderung der Wissenschaften e.V., Deutsche Forschungsgemeinschaft, to whom we are very grateful. Moreover the pharmaceutical industry gave assistance in the organization and the transcript of the pro­ ceedings. Dr. G~TZE of Springer-Verlag, was, as we will explain later, the original promotor of the idea for such a meeting. We should like to thank Springer-verlag for the excellent layout and quality of this book. Koln, Spring 1977 K.J. ZULCH, W. KAUFMANN K.-A. HOSSMANN, V. HOSSMANN Contents Welcome K.J. ZULCH xv Introduction W. KAUFMANN. XIX Coronary Circulation with Special Remarks on the Extra­ vascular Component of Resistance and on Collateral Flow W. LOCHNER, H. P. DIEMER, and J. WICHMANN. With 5 Figures.

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InhaltsangabeCoronary Circulation with Special Remarks on the Extravascular Component of Resistance and on Collateral Flow.- Vascular Reactivity and Ion Homeostasis in Heart and Brain.- Common Denominators in the Regulation of Blood Flow in Heart and Brain.- Oxygen Transport in Heart and Brain.- Regulation of Brain Energy Metabolism under Normoxic and Hypoxic Conditions.- Biochemistry and Contractility of the Infarcted Heart.- Regional Metabolism of the Brain.- Postischemic Amelioration of Brain Damage.- Coagulation Disturbances in Cerebrovascular Disorders.- Coagulation Disturbances in Ischemic Heart Disease.- Rheological Properties of the Blood under Normal and Pathological Conditions.- Total Ischemia of the Brain.- Experimental Ischemia: Total Ischemia of the Heart (Metabolic Recovery from Complete Anaerobiosis).- Microflow and Unit Activity in the Cerebral Cortex Following Ligation of the Middle Cerebral Artery.- Gradation of Ischemia with Threshold Flow Levels for Tissue Function and Structure in the Brain.- Experimental Ischemia: Heart Infarcts.- Distribution of Cerebral Blood Flow at Rest and During Mental Activation in Normals and in Patients with Brain Disorders.- The Heart in Hypertension.- Hypertension and Cerebral Blood Flow.- Hypotension as a Risk Factor.- Cardiac Embolism and Arterial Hypertension as Risk Factors of Cerebral Infarction.- Coronary Atherosclerosis and Ischemic Heart Disease.- Risk Factors: Comparison of the Biological Data in Myocardial and Brain Infarctions.- Cerebral Atherosclerosis: Morphology and Some Relationships with Coronary Atherosclerosis.- Experimental Cerebral Ischemia by Arachidonic Acid-Induced Platelet Emboli.- Transient Ischemic Events of the Heart-Angina Pectoris.- Transient Cerebral Ischemic Attacks (TIA'S).- Clinical Ischemia: Brain Infarcts.- Role of Thrombus in Causing Atherosclerosis and Fatal Coronary Heart Disease.- Therapy of Cerebrovascular Disorders.- Therapy of Myocardial Infarction and Coronary Heart Disease.- General Discussion.