Beschreibung
Immunomodulatory imbalance is the characteristic feature of autoimmune diseases like rheumatoid arthritis (RA). T helper (Th) 17 plays a critical role in the pathogenesis of RA. The balance of Th1 and Th17 is important for normal immune response. In RA therapy, methotrexate (MTX) has an important use depending on its anti-inflammatory effects, however, is limited due to its side effects. Curcumin is a natural plant product used as an immunomodulator. The aim of this study was to investigate the impact of curcumin and MTX administration singly or combined on a rat model with collagen-induced arthritis.
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Hersteller:
BoD - Books on Demand
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DE 22848 Norderstedt
Autorenportrait
Prof. Dr. Amany El-Wakkad is a professor immunology at Department of Medical Physiology, National Research Centre. Dr. Abeer Badr is an assistant professor of immunology at Department of Zoology, Faculty of Science, Cairo University. Elshaimaa Mohsen received her Ph.D. in immunology from Faculty of Science at Cairo University.